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Neurofibromatosis also increases the risk of leukemia particularly in children; Children with NF-1 have 200 to 500 times the normal risk of developing leukemia compared to the general population.

The disorder affects all neural crest cells (Schwann cells, melanocytes and endoneurial fibroblasts).

Cellular elements from these cell types proliferate excessively throughout the body, forming tumors; melanocytes also function abnormally in this disease, resulting in disordered skin pigmentation and “cafe-au-lait” spots.

Saya harap tulisan ini dapat menamba H wawasan pembaca,sekaligus mencegah kelainan menjadi anomali yang sangat parah seperti yang dilaporkan oleh sejawat dari Amerika Serikat. Juni 2011 Dr Iwan suwandy, MHA ENGLISH VERSION: Neurofibromatosis is a disorder (anomaly or Osis) Medical from the growing tissue (fibro) nerve (neuro) new (neoplasms or tumors) are abnormal, though it may be benign, but malignant demaged caused the body and face posture ‘s demage .

Without view the patients directly, you definitely will not be imaging how the appearance of the patient, for a light I’ve ever seen as the body with swelling of skin tissue that is very much like a like a tree with hanging fruit, but in extreme cases look like a human monster, the case This new reported by the physician experts tumor (Oncology) from the Hospital (Hospital) in the United States, there are two reported cases.

Approximately half of cases are due to ) is the most common form of NF, accounting for up to 90% of the cases.

NF 1 has a disorder frequency of 1 in 4,000, making it more common than neurofibromatosis type 2, with a frequency of 1 in 45,000 people.

This grouping is an artifact of an earlier time in medicine, before the distinct genetic basis of each of these diseases was understood.